Apply for active substance renewal by the deadlines to keep products on the GB market Under the GB Biocidal Products Regulation (GB BPR), active substance approvals will expire unless a renewal application is submitted at least 550 days before their expiry date. The 550-day deadlines are coming up for the following active substance/product type combinations under GB BPR: - (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol (Cholecalciferol) (CAS 67-97-0 EC 200-673-2) in product type 14
28 December 2022
- (RS)-4-hydroxy-3-(3-oxo-1-phenylbutyl)coumarin (Warfarin) (CAS 81-81-2 EC 201-377-6) in product type 14
28 December 2022
- 3-(3-biphenyl-4-yl-1,2,3,4-tetrahydro-1-naphthyl)-4-hydroxycoumarin (Difenacoum) (CAS 56073-07-5 EC 259-978-4) in product type 14
28 December 2022
- 3-[3-(4'-Bromo[1,1'-biphenyl]-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2H-1-benzopyran-2-one (Bromadiolone) (CAS 28772-56-7 EC 249-205-914 ) in product type 14
28 December 2022
- 3-[3-(4′-bromo[1,1′biphenyl]-4-yl)-1,2,3,4-tetrahydronaphth-1-yl]-4-hydroxy-2H-1-benzothiopyran-2-one (Difethialone) (CAS 104653-34-1 EC n/a) in product type 14
28 December 2022
- 3-[3-(4'-bromobiphenyl-4-yl)-1,2,3,4-tetrahydro-1-napthyl]-4-hydroxycoumarin (Brodifacoum) (CAS 56073-10-0 EC 259-980-5) in product type 14
28 December 2022
- 4-hydroxy-3-[(1RS,3RS;1RS,3RS)-1,2,3,4-tetrahydro-3-[4-(4-trifluoromethylbenzyloxy)phenyl]-1-naphthyl]coumarin (Flocoumafen) (CAS 90035-08-8 EC 421-960-014) in product type 14
28 December 2022
- Chlorophacinone (CAS 3691-35-8 EC 223-003-0) in product type 14
28 December 2022
- Coumatetralyl (CAS 5836-29-3 EC 227-424-0) in product type 14
28 December 2022
- Polyhexamethylene biguanide hydrochloride with a mean number-average molecular weight (Mn) of 1600 and a mean polydispersity (PDI) of 1.8 (PHMB (1600;1.8)) (CAS 27083-27-8 / 32289-58-0 EC n/a) in product types 2, 3 and 11
28 December 2022
- 1-(4-chlorophenyl)-4,4-dimethyl-3-(1,2,4-triazol-1-ylmethyl)pentan-3-ol (Tebuconazole) (CAS 107534-96-3 EC 403-640-2) in product types 7 and 10
28 December 2023
- 2-bromo-ethanoic acid (Bromoacetic acid) (CAS 79-08-3 EC 201-175-8) in product type 4
28 December 2023
- 3-iodo-2-propynylbutylcarbamate (IPBC) (CAS 55406-53-6 EC 259-627-5) in product type 6
28 December 2023
- 3-phenoxybenzyl-2-(4-ethoxyphenyl)-2-methylpropylether (Etofenprox) (CAS 80844-07-1 EC 407-980-2) in product type 18
28 December 2023
- Benzoic acid (CAS 65-85-0 EC 200-618-2) in product types 3 and 4
28 December 2023
- Copper sulphate pentahydrate (CAS 7758-99-8 EC 231-847-6) in product type 2
28 December 2023 Any person, company or taskforce/consortium can support an active substance/product type combination for renewal – it doesn't have to be the original supporter. Check the GB Article 95 List to see who the original supporters were If a renewal application is not submitted for the above active substance/product type combinations under GB BPR, the approvals will expire. This means the active substances can no longer be used in biocidal products of the relevant product types in Great Britain. Make sure you are receiving important information about your product authorisations and approvals If you hold product authorisations and approvals in Great Britain under the GB BPR or the Control of Pesticides Regulations (COPR), you should make sure HSE has the right contact details for you. If the details we hold are out of date, you may not receive important information about your product authorisation or approval. Update your details | 
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